構造生物薬学分野

Sakamoto, Y., Roppongi, S., Suzuki, Y., Ishihara, T., Hidaka, K., Nakamura, N., Honma N., Ogasawara W., Tanaka N. The crystal structure of peptidase toward drug discovery. Int. J. Microgravity Sci. Appl. 2019p360106 (2019)

Yoshida, Y., Sato, M., Nonaka, T., Hasegawa, Y., and Kezuka, Y. Characterization of the phosphotransacetylase-acetate kinase pathway for ATP production in Porphyromonas gingivalis. J. Oral Microbiol. 11, 1588086 (2019)

Xiang, H., Okamura, H., Kezuka, Y., and Katoh, E. Physical and thermodynamic characterization of the rice gibberellin receptor/gibberellin/ DELLA protein complex. Sci. Rep. 8, 17719 (2018)

Kezuka, Y., Ishida, T., Yoshida, Y., and Nonaka, T. Structural insights into the catalytic mechanism of cysteine (hydroxyl) lyase from the hydrogen-sulfide producing oral pathogen, Fusobacterium nucleatum. Biochem. J. 475 (4), 733-748 (2018)

Sekiya, M., Sakamoto, Y., Futai, M., Nakanishi-Matsui, M. Role of α/β interface in F1 ATPase rotational catalysis probed by inhibitors and mutations. Int J Biol Macromol. 99, 615-621 (2017)

Roppongi, S., Suzuki, Y., Tateoka, C., Fujimoto, M., Morisawa, S., Iizuka, I., Nakamura, A., Honma, N., Shida, Y., Ogasawara, W., Tanaka, N., Sakamoto, Y., Nonaka, T. Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues. Sci. Rep. 8 (1), 2714 (2018)

Jamal, N., Kezuka, Y., Nonaka, T., Ohashi, K. and Nata, K. Recombinant Human REG Iα aggregates Staphylococcus aureus – Exhibits a lectin-like function. Adv. Biosci. Biotech. 8, 79-90 (2017)

阪本泰光、野中孝昌、鈴木義之、小笠原渉、田中信忠 糖非発酵グラム陰性細菌由来新規ジペプチド産生酵素の構造と機能、日本結晶学会誌、58、221-227(2016)

Ishibashi, K., Kezuka, Y., Kobayashi, C., Kato, M., Inoue, T., Nonaka, T., Ishikawa, M., Matsumura, H. and Katoh, E. Structural basis for the recognition-evasion arms race between Tomato mosaic virus and the resistance gene Tm-1. Proc. Natl. Acad. Sci. USA 111(33), E3486-3495. (2014)

野中孝昌 大学発の創薬への挑戦 日本医学物理学会第116回学術大会、盛岡市、2018年9月