創薬有機化学分野

【2021原著論文01】"Catalytic and Diastereoselective Cascade Reaction for the Preparation of cis-1,3-Disubstituted Isoindoline-Aminal Hybrid Compounds", Tetsuya Tsujihara, Takeyuki Suzuki, Tomikazu Kawano
Heterocycles, 102, 723-730 (2021). DOI: 10.3987/COM-21-14404

【2020原著論文07】“IMU1003, an atrarate derivative, inhibits Wnt/β-catenin signaling”, Honami Yonezawa, Aoi Sugawara, Tomoko Sakyo, Yoshimasa Uehara, Tomikazu Kawano, Naoyuki Nishiya*, Biochem. Biophys. Res. Commun., 532, 440-445 (2020). DOI: https://doi.org/10.1016/j.bbrc.2020.08.031

【2020学会02】“アルキル源としてカルボン酸を用いる新規 N-アルキル化法の適用性”, 〇佐藤圭悟、田村 理、菅原 葵、佐藤絵理花、佐藤風薫、高橋俊介、河野富一, 第31回万有仙台シンポジウム, 仙台(オンライン), 令和2年10月17日 (2020)

【2020学会01】<招待講演>“活性天然物の合成と作用メカニズムに基づいた類縁体設計および合成”, 〇田村理, 有機合成化学協会東北支部岩手地区講演会, 盛岡, 令和2年9月28日 (2020)

【2020その他01】"グルココルチコイド受容体阻害剤”, 発明者: 清水康晴・堀厚・上田実・田村理*, 出願番号2020-164943、2020.9.30出願

【2020原著論文06】“Toosendanin relatives, trypanocidal principles from Meliae Cortex”, Michel N Mifundu, Nobutoshi Murakami, Tomikazu Kawano, Satoru Tamura*, J. Nat. Med., 74, 702-709 (2020). DOI: https://doi.org/10.1007/s11418-020-01422-9

【2020原著論文05】“Synthesis and biological evaluation of new cur cumin analogs inhibiting osteoclastogenesis”, Aoi Sugawara, Toshika Ohashi, Satoshi Ogawa, Naomi Matsumoto, Mayumi Nakanishi-Matsui, Satoru Tamura, Tomikazu Kawano*, Heterocycles, 100, 1233-1247 (2020). DOI: 10.3987/COM-20-14282

【2020原著論文04】"Structure activity relationship of anti-malarial allylpyrocatechol isolated from Piper betle”, Satoru Tamura*, Akihito Miyoshi, Tomikazu Kawano, Toshihiro Horii, Sawako Itagaki, Nobutoshi Murakami, Chem. Pharm. Bull. 68, 784-790 (2020). DOI: https://doi.org/10.1248/cpb.c20-00294

【2020原著論文03】“Diastereoselective direct amidation/aza-Michael cascade reaction to synthesize cis-1,3-disubstituted isoindolines”, Tetsuya Tsujihara*, Hazuki Yamauchi, Satoru Tamura, Tsunayoshi Takehara, Takeyuki Suzuki, Tomikazu Kawano*, Tetrahedron Lett., 61, 152122 (2020). DOI:https://doi.org/10.1016/j.tetlet.2020.152122

【2020原著論文02】“Identification of Chemical Structures of Hypolipidemic Proanthocyanidins
in Red Rice Enhancing Acyl CoA Oxidase Expression”, Satoru Tamura, Ke Yan, Tomikazu Kawano, Mayumi Ohnishi-Kameyama, Junji Tanaka, Hiroshi Shimoda* and Nobutoshi Murakami, J Rice Res 8: 213.