薬物代謝動態学分野

Shogo Ozawa, Toshitaka Miura, Jun Terashima, Wataru Habano and Seiichi Ishida
Recent progress in prediction systems for drug-induced liver injury using in vitro cell culture Drug Metabolism Letters 2021, 14, 25-40

Taichi Ishikawa, Jun Terashima, Yu Shimoyama, Yu Ohashi, Toshinari Mikami, Yasunori Takeda and Minoru Sasaki
Effects of butyric acid, a bacterial metabolite, on the migration of ameloblastoma mediated by laminin 332 Journal of Oral Science In press

Jimma, Y., Jimma, K., Yachi, M., Hakata, S., Habano, W., Ozawa, S., Terashima, J.: Aryl hydrocarbon receptor mediates cell proliferation enhanced by benzo[a]pyrene in human lung cancer 3D spheroids. Cancer Investigation 2019; 37(8):367-375.

三浦利貴,幅野渉,寺島潤,小澤正吾:デコイを用いたAhR経路へのエピゲノムの関与の解析方法の確立.日本薬学会第139年会.千葉.平成31年3月23日

Hakata, S., Terashima, J., Shimoyama, Y., Okada, K., Fujioka, S., Ito, E., Habano, W., Ozawa, S.: Differential sensitization of two human colon cancer cell lines to the antitumor effects of irinotecan combined with 5-aza-2’-deoxycytidine. Oncol. Lett. 15, 4641-4648, 2018.

Sugai, T., Takahashi, Y., Eizuka M., Sugimoto, R., Fujita, Y., Habano, W., Otsuka, K., Sasaki, A., Yamamoto, E., Matsumoto, T., Suzuki, H.: Molecular profiling and genome-wide analysis based on somatic copy number alterations in advanced colorectal cancers. Mol Carcinog. 57, 451-461, 2018.

Sugai, T., Eizuka, M., Arakawa, N., Osakabe, M., Habano, W., Fujita, Y., Yamamoto, E., Yamano, H., Endoh, M., Matsumoto, T., Suzuki, H.: Molecular profiling and comprehensive genome-wide analysis of somatic copy number alterations in gastric intramucosal neoplasias based on microsatellite status. Gastric Cancer. 21, 765-775, 2018

Sugai, T., Eizuka, M., Habano, W., Fujita, Y., Sato, A., Sugimoto, R., Otsuka, K., Yamamoto, E., Matsumoto, T., Suzuki, H.: Comprehensive molecular analysis based on somatic copy number alterations in intramucosal colorectal neoplasias and early invasive colorectal cancers. Oncotarget 9, 22895-22906, 2018.

Sugai, T., Habano, W., Eizuka, M., Uesugi, N., Osakabe, M., Suga, Y., Nagasawa, T., Itamochi, H., Sugiyama, T.: Molecular landscape of copy number alterations and genetic mutations in high-grade serous adenocarcinoma of the ovary. J Iwate Med Association. 70, 125-38, 2018.

Terashima, J., Jimma, Y., Jimma, K., Hakata, S., Yachi, M., Habano, W., Ozawa, S.: The regulation mechanism of AhR activated by benzo[a]pyrene for CYP expression are different between 2D and 3D culture of human lung cancer cells. Drug. Metab. Pharmacokinet. 33 211-214, 2018.