天然物化学分野

Ryosuke Tanaya, Takeshi Kodama, Yuan-E Lee, Yoko Yasuno, Tetsuro Shinada, Hironobu Takahashi, Takuya Ito, Hiroyuki Morita, Suresh Awale, and Futoshi Taura* Catalytic Potential of Cannabis Prenyltransferase to Expand Cannabinoid Scaffold Diversity. Organic Letters 2023, 25, 8601–8605

浅野孝:機能性ファイトケミカルの効率的生産を目指した植物細胞培養系の構築(日本薬学会東北支部 第20 回生物化学若手研究者セミナー、オンライン、2022年10月22日)

Naoko Yoshimoto#, Takashi Asano#, Ayuna Kisanuki, Chihiro Kanno, Machiko Asanuma, Mami Yamazaki, Isao Fujii, Kazuki Saito (#equall contribution):
The ability of callus tissues induced from three Allium plants to accumulate health-beneficial natural products, S-alk(en)ylcysteine sulfoxides. J. Nat. Med., 76, 803-810 (2022).

Taisuke Matsuo, Takashi Asano, Yuki Mizuno, Shuri Sato, Ibuki Fujino, Yasuyuki Sadzuka:
Water spinach and okra sprouts inhibit cancer cell proliferation. In Vitro Cell Dev. Biol. Anim., 58, 79-84 (2022).

Ryo Nakabayashi, Yutaka Yamada, Tomoko Nishizawa, Tetsuya Mori, Takashi Asano, Masanari Kuwabara, Kazuki Saito:
Tandem Mass Spectrum Similarity-Based Network Analysis Using 13C-Labeled and Non-labeled Metabolome Data to Identify the Biosynthetic Pathway of the Blood Pressure-Lowering Asparagus Metabolite Asparaptine A. J. Agric. Food Chem., 69, 8571-8577 (2021)

浅野孝:“岩手医科大学薬用植物園”:落合知子(編集)、“医学・歯学・薬学系博物館事典”、雄山閣出版、2021年5月

Isao Fujii, Makoto Hashimoto, Kaori Konishi, Akiko Unezawa, Haruka Sakuraba, Kenta Suzuki, Harue Tsushima, Miho Iwasaki, Satsuki Yoshida, Akane Kudo, Rina Fujita, Aika Hichiwa, Koharu Saito, Takashi Asano, Jun Ishikawa, Daigo Wakana, Yukihiro Goda, Ayumi Watanabe, Mamoru Watanabe, Yui Masumoto, Junichiro Kanazawa, Hajime Sato, Masanobu Uchiyama: Functional Analysis of a Biosynthetic Gene Cluster Demonstrates Role of Spontaneous Double Bicyclo‐ring Formation Including 8π–6π Electrocyclization in Shimalactone Biosynthesis. Angew. Chem. Int. Ed., 59, 8464-8470 (2020).

Makoto Hashimoto, Hitomi Ichijo, Kotaro Fujiwara, Hitoshi Sugasawa, Seika Abo, Kimihito Matsudo, Nahoko Uchiyama, Yukihiro Goda, Isao Fujii: Functional expression of a highly-reducing polyketide synthase of Emericella variecolor IFM42010, an asteltoxin-producing strain, resulted in production of two polyenoic β-ketolactones with opposite stereochemistry. Bioorg. Med. Chem. Lett., 29, 126686 (2019).

Ryo Nakabayashi, Tomoko Nishizawa, Tetsuya Mori, Hiroshi Sudo, Isao Fujii, Takashi Asano, Kazuki Saito: Evaluating the sulfur-containing metabolite asparaptine in Asparagus calluses and a suspension cell line by untargeted metabolome analysis using liquid chromatography tandem mass spectrometry. Plant Biotech., 36, 265-267 (2019).