天然物化学分野

Hiroaki Hayashi, Musavvara Shukurova, Shihoko Oikawa, Minami Ohta, Isao Fujii, Firuza Nasyrova, Kurbon Aliev, Hikmat Hisoriev, Inoyat Fattokhov, Madibron Saidov: Field Survey of Ephedra Plants in Central Asia (1). Characterizationof Ephedra equisetina, Ephedra intermedia, and Their Putative Hybrids. Biol. Pharm. Bull., 42, 552-556 (2019).

Hiroaki Hayashi, Keiko Yokoshima, Ren Chiba, Isao Fujii, Inoyat Fattokhov, Madibron Saidov: Field Survey of Glycyrrhiza Plants in Central Asia (5). Chemical Characterization of G. bucharica Collected in Tajikistan. Chem. Pharm. Bull, 67, 534-539 (2019).

Mio Kawaguchi, Taichi Ohshiro, Masayuki Toyoda, Satoshi Ohte, Junji Inokoshi, Isao Fujii, Hiroshi Tomoda: Discovery of a Fungal Multicopper Oxidase That Catalyzes the Regioselective Coupling of a Tricyclic Naphthopyranone To Produce Atropisomers. Angewandte Chemie Int. Edt., 57, 5115-5119 (2018).

Ayako Katsuki, Hikaru Kato, Yurika Tahara, Makoto Hashimoto, Isao Fujii, Sachiko Tsukamoto: pH-Dependent production of himeic acid A and its non-enzymatic conversions to himeic acids B and C. Bioorg. Med. Chem., 26, 1869-1874 (2018).

Makoto Hashimoto, Hikaru Kato, Ayako Katsuki, Sachiko, Tsukamoto, Isao Fujii: Identification of the biosynthetic gene cluster for himeic acid A, a ubiquitin-activating enzyme (E1) inhibitor, in Aspergillus japonicus. ChemBioChem, 19, 535-539 (2018).

浅野 孝:植物と微生物の共生によるアルカロイド生合成研究の新展開. ファルマシア, 53, 1113 (2017).

Hiroaki Hayashi, Shinya Tamura, Ren Chiba, Isao Fujii, Nobuji Yoshikawa, Inoyat Fattokhov, Madibron Saidov: Field Survey of Glycyrrhiza Plants in Central Asia (4). Characterization of G. glabra and G. bucharica Collected in Tajikistan. Biol. Pharm. Bull., 39, 1781-1786 (2016).

Nobuyuki Kashiwa, Yutaka Ebizuka, Isao Fujii: Identification and Heterologous Expression of the Topopyrone Nonaketide Synthase Gene from Phoma sp. Chem. Pharm. Bull., 64, 947-951 (2016).

Ryuya Fujii, Takahiro Ugai, Hirofumi Ichinose, Mayumi Hatakeyama, Takuto Kosaki, Katsuya Gomi, Isao Fujii, Atsushi Minami, Hideaki Oikawa: Reconstitution of biosynthetic machinery of fungal polyketides: Unexpected oxidations of intermediates by expression host. Biosci. Biotech. Biochem., 80, 426-431 (2016).

Koji Narita, Ryota Chiba, Atsushi Minami, Motoichiro Kodama, Isao Fujii, Katsuya Gomi, Hideaki Oikawa: Multiple oxidative modifications in the ophiobolin biosynthesis: P450 oxidations found in the genome mining. Organic Letters, 18, 1980-1983 (2016).